You are probably here looking for a chart. We are not going to give you one, and this article explains why, and what actually determines the number on your dog’s prescription.

Why we do not publish a dosing chart

A chart looks like information. What it actually is, in this context, is a prescription written for a dog nobody has examined.

A published dose cannot know your dog’s kidney values. It cannot know about the NSAID they have been on for two years, the mass your vet is monitoring, or the fact that “65 pounds” is a guess from 2024. It cannot know whether you are trying to get a dog through an eight-week recovery window or keep an eleven-year-old comfortable for another two years, which are different doses of the same compound.

Sites that publish dosing tables are, functionally, letting you self-prescribe while keeping the liability at arm’s length. We would rather explain the reasoning and then have a veterinarian apply it to your actual dog.

Weight is the starting point, not the answer

Peptide dosing is weight-based in the sense that a 12-pound terrier and a 110-pound mastiff are not getting the same amount. Dose is generally expressed per kilogram of body weight, and your dog’s weight sets the baseline range.

Then it gets adjusted. Here is what for.

The target tissue

A protocol aimed at a specific injured tendon is dosed differently from one aimed at systemic inflammation. Local versus systemic goals change both the amount and, sometimes, the route.

Acute versus maintenance

Recovery protocols typically run higher for a defined window, often eight to twelve weeks, and then taper or stop. Chronic maintenance protocols for arthritis run lower and continue longer. Same compound, materially different number.

Route

Oral and injectable delivery do not produce the same systemic availability, so the same therapeutic goal requires different amounts depending on how it is given.

Organ function

Reduced kidney or liver function changes clearance. In senior dogs this is often the single biggest modifier, and it is why your veterinarian asks harder questions about a senior dog’s history before writing a protocol.

Everything else your dog is taking

Not because peptides interact dangerously with most common medications, the interaction profile is relatively quiet, but because the whole picture determines whether a protocol makes sense at all, and at what intensity.

How your dog responds

This is the one owners underestimate. The starting dose is a hypothesis. The day-30 check-in exists to test it. Many dogs end up somewhere other than where they started, and a protocol that never gets revisited is being managed badly.

What the process looks like at Revive

  1. Intake. Weight, age, breed, diagnosis, medications, any records you have, and what you are actually trying to change.
  2. Consult. A licensed veterinarian goes through it with you, screens for exclusions, and asks the things the form did not.
  3. The prescription. A specific compound or combination, a specific dose, a specific schedule, written for your dog.
  4. Day 30. A structured check-in. Hold, adjust, or stop.
  5. Ongoing review. Quarterly on most protocols; monthly on complex ones.

Practical dosing questions

What if I miss a dose? Give it when you remember unless it is nearly time for the next one, in which case skip it. Do not double up.

Can I give it with food? Usually yes, and for oral protocols it is often preferred, it reduces the mild GI upset some dogs get in the first week. Your protocol will say.

What if my dog gains or loses weight? Tell your care team. A 15% change in body weight is worth a dose review, and weight changes are common in dogs whose mobility improves.

Can I increase the dose if it is not working? No. Talk to your veterinarian. “More” is sometimes the right answer, and sometimes the right answer is that this is not working and you should stop, which more will not fix.

The uncomfortable part

We would rather you booked a consult than took a number off a webpage. That is an obvious commercial interest and we are not going to pretend it is not.

But the reason still holds independently: dosing a compounded preparation for an unexamined animal is not a thing a chart can responsibly do. If you decide to go elsewhere, go somewhere that has a veterinarian looking at your dog.

Keep reading

This article is educational and is not veterinary advice. Peptide protocols referenced here are compounded preparations, are not FDA-approved animal drugs, and are dispensed only on a patient-specific prescription from a licensed veterinarian. Always consult your own veterinarian before starting, stopping, or changing any treatment.